Background
Corey, Elias James was born on July 12, 1928 in Methuen, Massachusetts, United States. Son of Elias and Tina (Hashem) Corey.
(The Logic of Chemical Synthesis The title of this three-p...)
The Logic of Chemical Synthesis The title of this three-part volume derives from a key theme of the book-the logic underlying the rational analysis of complex synthetic problems. Although the book deals almost exclusively with molecules of biological origin, which are ideal for developing the fundamental ideas of multistep synthetic design because of their architectural complexity and variety, the approach taken is fully applicable to other types of carbon-based structures. Part One outlines the basic concepts of retrosynthetic analysis and the general strategies for generating possible synthetic pathways by logical reduction of molecular complexity. Systematic retrosynthetic analysis and the concurrent use of multiple independent strategies to guide problem solving greatly simplify the task of devising a new synthesis. This way of thinking has been used for more than two decades by one of the authors to teach the analysis of difficult synthetic problems to many hundreds of chemists. A substantial fraction of the intricate syntheses which have appeared in the literature in recent years have been produced by these individuals and their students. Part Two, a collection of multistep syntheses, provides much integrated information on synthetic methods and pathways for the construction of interesting target molecules. These syntheses are the result of synthetic planning which was based on the general principles summarized in Part One. Thus, Part Two serves to supplement Part One with emphasis on the reactions of synthesis and on specific examples of retrosynthetically planned syntheses. Part Three is intended to balance the coverage of Parts One and Two and to serve as a convenient guide to the now enormous literature of multistep synthesis. Information on more than six hundred interesting multistep syntheses of biologically derived molecules is included. It is hoped that the structural range and variety of target molecules presented in Part Three will appeal to many chemists.
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( Written by world-renowned and best-selling experts, Nob...)
Written by world-renowned and best-selling experts, Nobel Laureate E. J. Corey and Laszlo Kurti, Enantioselective Chemical Synthesis offers an authoritative and comprehensive overview of the field’s progress; the processes and tools for key formations; future development for complex, stereocontrolled (enantiomeric or diastereoisomeric) molecules; and valuable examples of multi-step syntheses. Utilizing a color-coded scheme to illustrate chemical transformations, Enantioselective Chemical Synthesis provides clear explanation and guidance through vital asymmetrical syntheses and insight into the next steps for the field. Researchers, professionals, and academics will benefit from this valuable, thorough, and unique resource. • In Part I, the authors present clearly, comprehensively and concisely the most useful enantioselective processes available to synthetic chemists. • Part II provides an extensive discussion of the most logical ways to apply these new enantioselective methods to the planning of syntheses of stereochemically complex molecules. This hitherto neglected area is essential for the advancement of enantioselective synthesis to a more rational and powerful level. • Part III describes in detail many reaction sequences which have been used successfully for the construction of a wide variety of complex target molecules • Clearly explains stereochemical synthesis in theory and practice • Provides a handy tool box for scientists wishing to understand and apply chiral chemical synthesis • Describes almost 50 real life examples of asymmetric synthesis in practice and examines how the chiral centers were introduced at key synthetic stages
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(Molecules and Medicine provides, for the first time ever,...)
Molecules and Medicine provides, for the first time ever, a completely integrated look at chemistry, biology, drug discovery, and medicine. It delves into the discovery, application, and mode of action of more than one hundred of the most significant molecules in use in modern medicine. Opening sections of the book provide a unique, clear, and concise introduction, which enables readers to understand chemical formulas.
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Corey, Elias James was born on July 12, 1928 in Methuen, Massachusetts, United States. Son of Elias and Tina (Hashem) Corey.
Bachelor of Science, Massachusetts Institute of Technology, 1948. Doctor of Philosophy, Massachusetts Institute of Technology, 1951. AM (honorary), Harvard University, 1959.
Doctor of Science (honorary), University Chicago, 1968. Doctor of Science (honorary), Hofstra University, 1974. Doctor of Science (honorary), Colby College, 1976.
Doctor of Science (honorary), Oxford University, 1982. Doctor of Science (honorary), University Liege, 1985. Doctor of Science (honorary), University Illinois, 1985.
Doctor of Science (honorary), Kenyon College, 1989. Doctor of Science (honorary), Helsinki College, 1990. Doctor of Science (honorary), Arizona University, 1990.
Doctor of Science (honorary), Merrimac College, 1990. Doctor of Science (honorary), Hokkaido University, 1991. Doctor of Science (honorary), Rennselaer Polytechnic Institute, 1991.
Doctor of Science (honorary), Boston College, 1992. Doctor of Science (honorary), Texas Agricultural and Mechanical University, 1997. Doctor of Science (honorary), National Chung Cheng University, 1999.
Doctor of Science (honorary), University Alicante, 1999. Doctor of Science (honorary), Cambridge University, 2000.
Assistant Professor, of Chemistry 1953-1955, Professor 1956-1959. Sheldon Emery Professor, of Chemistry, Harvard University since 1959, Chairman Department, of Chemistry 1965-1968. Alfred P. Sloan Foundation Fellow 1955-1957, Guggenheim Fellow 1957, 1968-1969.
(The Logic of Chemical Synthesis The title of this three-p...)
(Molecules and Medicine provides, for the first time ever,...)
( Written by world-renowned and best-selling experts, Nob...)
Co-author: The Logic of Chemical Synthesis, 1995, Molecules and Medicine, 2008. Editorial board member Journal Organic Chemistry, 1962-1965. Contributor articles to professional journals.
Fellow: American Association for the Advancement of Science. Member: National Academy of Sciences (Award in chemical science 2002), Royal Society London (foreign), Institute Medicine, Robert A. Welch Foundation, Franklin Institute, American Academy Arts & Sciences, Society Synthetic Organic Chemistry (honorary), Pharmaceutical Society Japan (honorary), Chemical Society Finland (honorary), Royal Society Chemistry (honorary Robert Robinson Medal 1988), Chemical Society Japan (honorary), American Chemical Society (honorary Pure Chemistry award 1960, Fritzche award 1968, Synthetic Chemistry award 1971, Harrison Howe award 1971, Remsen award 1974, Arthur C. Cope award 1976, Willard Gibbs award 1984, Madison Marshall award 1985, Roger Adams award 1993, Priestly medal 2004), Sigma Xi.
Outdoor activities and music.
Married Claire Higham, September 14, 1961. Children: David, John, Susan.