Bachelor, University California, Berkeley, 1958. Doctor of Medicine, University Rochester, 1951.
Member staff Children's Hospital, Los Angeles, 1952—1975, 1977—2003, director child development division, 1955-1975. Deputy director California Department Health, 1975-1976. Professor pediatrics University Southern California, 1955—1975, 1977—2003.
Director Phenylketonuria Collaborative Study, 1966-1982. Medical director Spastic Children's Foundation, Los Angeles, 1980-1985. Member Project Hope, Trujillo, Peru, 1970.
Director Regional Center for Developmentally Disabled at Children's Hospital, Los Angeles, 1966-1975. Member research advisory board National Association Retarded Citizens, 1974-1976. Member Governor's Council on Development Disabilities, 1981-1983.
Board directors Down's Syndrome Congress, 1974-1976. Principal investigator Maternal Phenylketonuria Project National Institute Child Health and Human Development, Washington, 1985-2003. Member forensic assessment team South Central Regional Center for Developmental Disabilities, since 1999.
(Book by Richard Koch, James Dobson)
Member American Association on Mental Deficiency (president 1968-1969), American Academy Pediatrics, Society for Study Inborn Errors Metabolism, Society Inborn Metabolic Disorders, Sierra Club (treasurer Mineral King task force 1972).
Married Kathryn Jean Holt, October 2, 1943. Children: Jill, Thomas, Christine, Martin, Leslie.