He graduated Bachelor of Arts in 1715, and Master of Arts
He received his education at Kensington. He was admitted a commoner of Wadham College, Oxford on 12 April 1712, where he was subsequently elected a scholar. 13 June 1718. In July 1719 he was transferred to Hart Hall, and soon afterwards took holy orders.
In 1722 he was chosen fellow of Dulwich College.
He was a favourite with John Robinson, the bishop of London, with whom he resided for about two years. On the resignation of Joseph Butler, Bolton became preacher at the Rolls Chapel in London, 1729, on the nomination of Sir Joseph Jekyll.
As fellow of Dulwich College, Bolton took up residence there on 10 March 1722, but resigned his fellowship on 1 May 1725. He then moved to Kensington, depending mainly on his personal fortune, and became close to William Whiston, from he had introductions to both Jekyll and Lord Hardwicke.
Bolton was preferred to the deanery of Carlisle, and admitted 1 February 1735.
Later (1738) he was instituted vicar of Saint Mary"s, Reading. He held both benefices together for life, and was non-resident in his deanery. He raised some money to add to poor livings in the diocese of Carlisle.
Bolton died in London on 26 November 1763, having come to town to consult Doctor Anthony Addington.
He was buried in the church-porch of Saint Mary"s, Reading.