Contributions From The Pathological Laboratory ...: Reprints, Volume 7...
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This is a reproduction of a book published before 1923....)
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Contributions From The Pathological Laboratory ...: Reprints, Volume 7
University of Michigan. Pathological Laboratory, Alfred Scott Warthin
Pathology
Aldred Scott Warthin was an American pathologist whose research laid the foundation for understanding the heritability of certain cancers.
Background
Aldred Scott Warthin was born in Greensburg, Ind. The son of Edward Mason and Eliza Margaret (Weist) Warthin, he came of English and Pennsylvania Dutch ancestry. His grandfather was one of the first settlers in Decatur County, Ind. , where he set up a general store; his maternal grandmother, also, had journeyed to the frontier. With an uncle, a physician interested in the study of nature, he went afield collecting specimens; and to please his invalid mother he took lessons on the piano.
Education
Considered a prodigy by his neighbors, he entered the Cincinnati Conservatory of Music and in 1887 gained a teacher's diploma. During the same period he studied at the University of Indiana under David Starr Jordan, and upon receiving the degree of A. B. in 1888, he turned to science.
Career
Already he had taught botany. His decision caused his father to withhold further aid. Characteristically undaunted, he enrolled in the medical department of the University of Michigan, and, supporting himself by giving music lessons and serving as church organist, graduated with the degree of M. D. in 1891. His potential value to the medical school as a teacher was recognized by the new professor of medicine, George Dock. While assistant (1891) and demonstrator (1892 - 95), he learned clinical medicine, and in 1893 received the degree of Ph. D. In 1896 he was given charge of the work in pathology, taking over a department without material and replacing a teacher who believed that bacteria had no relation to disease. His intense energy and curiosity, already manifest in several scientific papers, now found scope. To procure material he arranged that all specimens from the clinics be sent to him, and his diagnostic findings soon became a touchstone for the practitioner, a relationship to clinical medicine which broadened throughout his life. At first he did the entire work of the laboratory which he created, technical and intellectual, teaching large classes, doing autopsies and research, instructing graduate students, holding seminars, and even giving a course in medical history. By 1903 he was professor and director. Warthin's summers from 1893 to 1900 were spent in the pathological laboratories of Freiburg, Dresden, and Vienna. In Vienna he came upon Durer's engraving of the knight riding unconcerned past a leering Devil and a bony Death; and ever after the morbid seemed to him thrice morbid because expressive of the human predicament. Working and writing on numerous themes, among them tuberculosis of the placenta, the hemolymph nodes - which he established as physiological entities - the cause of Banti's disease, heredity in cancer, traumatic lip'mia, and mustard gas poisoning, he came to the study of syphilis, and in some forty papers disclosed its responsibility for conditions previously unsuspected. His findings were often disputed, yet it came to be recognized that in general he was but little more positive than the facts. Warthin's European experiences made him keenly conscious that the contribution of medicine to American civilization was barely begun, and to further it he gave himself to the founding and support of societies and journals. Possessed of a terse, vivid style, he wrote extensively and was in demand as lecturer. He published Practical Pathology for Students and Physicians (1897, 1911) and General Pathology (1903, 1908), a translation of the German work of Ernst Ziegler. He also edited the Annals of Clinical Medicine (1924 - 31). He became president of several medical organizations, notably the Association of American Physicians (1928). Shortly before his death he wrote "Forty Years as a Clinical Pathologist, " which was published posthumously in the Journal of Laboratory and Clinical Medicine (July 1931). That concern for his kind which led Warthin to study syphilis intensively found other expression in The Creed of a Biologist (1930). In this volume he held that man need look no further for immortality than to his descendants, nor for a larger task than to better man. Still there would be old age and death, and to discover a right attitude toward these he studied the aging process and collected books and pictures dealing with the "Dance of Death, " a collection which he bequeathed to the University of Michigan. His book Old Age - the Major Involution (1929) is unsparingly comprehensive. In The Physician of the Dance of Death (1931) he comments on pictures which tell of the doctor's surroundings and behavior when Death lays hands on him. Its author did not have to gain this knowledge, for he died of coronary occlusion, deeming it but a trivial asthma. In 1927 there was published Contributions to Medical Science Dedicated to Aldred Scott Warthin, containing scientific papers from members of his thirty-five classes.
Achievements
He has been described as "the father of cancer genetics. " Adenolymphoma of the parotid gland, or papillary cystadenoma lymphomatosum, is better known as "Warthin's tumor"; he described two cases in 1929. The Warthin-Starry stain, a silver-based stain for spirochetes, is named for him. He discovered a species of snail that was named in his honor.
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This is a reproduction of a book published before 1923....)
Personality
Warthin was bright-eyed and fresh-colored, quick and strong. He was drastic yet kind, earnest yet cheerful, and most sensitive to beauty. Unpopular in his early years because of a trenchant sincerity, he lived to be widely appreciated without having relinquished it.
Interests
He loved music, gardens, books, and friends.
Connections
On June 27, 1900, he married Katharine Angell. They had four children.
