Student, Meinzinger Art School, Detroit, 1940-1944; student, Skowhegan (Maine) School Painting and Sculpture, summer 1946.
Twardowicz began practicing photography on a 1948 trip to Mexico, and during the 1950s and 1960s he developed his painting style, related to color field paintings and abstract expressionism. Stanley Twardowicz was married to Ann Twardowicz (1929–1973), also a well-known painter. Twardowicz also befriended Jack Kerouac, and published some of the only images of the writer in his final years.
Married Lillian Dodson, March 15, 1971.