Thomas Pitt Camelford was educated at Clare College, Cambridge.
Thomas Pitt Camelford sat in parliament from 1761 till 1784, siding against his uncle and following George Grenville, who was also a relative; and in 1784 he was raised to the peerage. He dabbled in architecture and the arts generally, and was a prominent figure in the artistic circles of his day. His son Thomas Pitt, 2nd Baron Camelford (1775 - 1804), who succeeded him in 1793, had an adventurous and misspent career in the navy, but is principally remembered for his death in a duel with Mr Best on the 10th of March 1804, the title becoming extinct.
In July 1771 Pitt married Anne Wilkinson, the younger daughter and coheiress of Pinckney Wilkinson.