Vaidyanatha Subrahmanyan graduated from Madras University. He did his Doctor of Science from University of London in 1927.
Vaidyanatha Subrahmanyan was professor at department of Biochemistry of Indian Institute of Science (IISc) in Bangalore in 1927-1948; planning officer and director at Central Food Technological Research Institute in Mysore in 1948; CSIR Emeritus Scientist; FAO Food Technologist in Philippines in 1964-1966; advise at Subsidiary Foods and Nutrition, Ministry of Food and Agriculture, Community Development and Cooperation, New Delhi in 1966-1969; also project-coordinator and director at Paddy Processing Centre, Tiruvaroor, Tamil Nadu in 1969-1979.
He was a fellow at Royal Institute of Chemistry in London, National Institute of Sciences of India, Institute of Chemistry and member of Indian Science Congress Association (Past-President, Chemistry Section) and many Govt. of India Committees.