Mrs. Wang was born on June 27, 1949 in New York, United States. She belonged to a family of affluent Chinese immigrants, who came to the United States in the mid-1940s. Her father, Cheng Ching Wang (Wang Chengqing), owned a company of medicines and mother, Florence Wu (Wu Chifang), used to work for United Nations as a translator. Her maternal grandfather is Fengtian clique warlord Wu Junsheng, who was killed by the Empire of Japan in the Huanggutun incident in 1928. Mrs. Wang has one younger brother, Kenneth.