biochemist professor researcher
Vitaly Nikolaevich Nikandrov was born on August 4, 1949, in the Grodno area of Belarus. His documented family relations include his mother, Tamara, and his father, Nicholas. He developed his professional career in Belarusian biomedical and physiological research, later combining research and university teaching.
Nikandrov studied at the Vitebsk Academy of Veterinary Medicine, where he completed an MDV qualification in 1971. He subsequently studied at Byelorussian State University, receiving a Doctor of Philosophy degree in 1975. In 1989 he obtained the qualification of Science Habilitation Doctor through the Higher Attestation Commission of the Union of Soviet Socialist Republics.
Nikandrov's career has focused on biochemical research, proteolysis, regulatory proteins and peptides, and the biological activity of plasminogen-related systems. He worked as a researcher at the Byelorussian Research Institute of Epidemiology and Microbiology from 1975 to 1978 and continued biochemical investigations there during the 1980s. His research at the institute included studies of streptokinase and its plasminogen-activating function. From the late 1980s he was associated with the Institute of Physiology of the National Academy of Sciences of Belarus in Minsk. In the laboratory of regulatory proteins and peptides, where his work continued through 2012, he studied proteolytic systems, biologically active peptides, plasminogen and streptokinase, and their effects on cells of nervous tissue. He served as head of the laboratory of regulatory proteins and peptides from 1998 to 2000 and held an associate professor position during the same period. His work included investigations of the trophic and protective effects of proteolysis-related proteins on cultured neurons and glial cells, as well as research into glycine receptors and neural-tissue metabolism. Nikandrov later became associated with Polessky State University in Pinsk as a professor. His subsequent research included proteolytic activity in Chlorella vulgaris, the effects of mineral compounds on algal cultures, and biochemical methods for studying proteolysis. His scientific output includes journal articles, review papers, a chapter on proteolysis research methods, and contributions to patents concerning mammalian and neural cell culture.
Conducted sustained biochemical research on streptokinase, plasminogen activation, and proteolytic regulation, including a proposed oxygen-dependent mechanism for the plasminogen-activating function of streptokinase.
Developed and applied biochemical approaches to the study of proteolytic processes in neural-tissue cell cultures, including investigations of the protective and trophic effects of plasminogen-related proteins and peptides.
Contributed to research on proteolysis, peptide inhibitors of proteases, glycine receptors in nervous tissue, and proteolytic activity in Chlorella vulgaris.
(Chapter co-authored with N. S. Pyzhova in the educational...)
2013Влияние биогенных фосфатов на расщепление белков протеиназами и функцию активаторов плазминогена
(Co-authored research article on the effects of inorganic ...)
2008(Co-authored study of synthetic fibrinogen fragments and t...)
2006Proteolytic activity changes of homogenates of Chlorella vulgaris cells and culture function-metabolic reorganizations at the growth in the MnCl2 presence
(Co-authored research on changes in proteolytic activity a...)
2018(Single-author study published in The International Journa...)
1992Inhibition of virus reproduction and proteinase activity by lupane and some other terpenes
(Co-authored study examining antiviral and proteinase-inhi...)
2002Способ культивирования перевиваемой клеточной линии нейробластомы IMR-32
(Co-inventor of Belarusian Patent BY 12585 concerning a me...)
2009Способ культивирования перевиваемой линии клеток млекопитающих
(Co-inventor of Belarusian Patent BY 8876 concerning a met...)
2006Способ культивирования перевиваемой линии клеток млекопитающих
(Co-inventor of Belarusian Patent BY 8877 concerning a met...)
2006(Review co-authored with T. V. Balashevich on glycine meta...)
2014Nikandrov has been associated with the Belarusian Biochemical Society, serving on its board of directors, and with the New York Academy of Sciences, the European Peptide Society, and the Belarusian Physiological Society.
Nikandrov's documented family connections include his mother, Tamara, and his father, Nicholas. His professional connections include long-term research associations with the Byelorussian Research Institute of Epidemiology and Microbiology, the Institute of Physiology of the National Academy of Sciences of Belarus, and Polessky State University.
