Mr. Lo studied law at Oxford University in England, receiving Master of Arts degree.
Mr. Lo was admitted to the Inner Temple in London. In 1912-1916 was a chief procurator of the Metropolitan Procuratorate-General in Peking. From 1916 till 1926 he was an associate director of the law codification bureau, in 1921 Minister of Justice, in 1922 Minister of Finance and President of the Supreme Court in Peking. In 1926 Wen-kan Lo reappointed Minister of Justice. From 1926 to 1927 he worked as a Director-General of the Customs Administration of Peking Government. Then, in 1928, he became Minister of Foreign Affairs under the late Chang Tso-lin's regime in Peking. In 1934 he was a Minister of Justice of the National Government. In summer 1933 he was a Special Commissioner to Sinkiang to investigate diplomatic situation on the Chinese-Russian Border. He was also director of the Whampoa Harbour Development Administration at Canton.