Background
Shealy, Y. Fulmer was born on February 26, 1923 in Chapin, South Carolina, United States. Son of L. Yoder and L. Essie (Fulmer) Shealy.
Shealy, Y. Fulmer was born on February 26, 1923 in Chapin, South Carolina, United States. Son of L. Yoder and L. Essie (Fulmer) Shealy.
Doctor of Philosophy, University of Illinois, 1949. Chemist Office of Science Research and Development, 1943-1945. Postdoctoral fellow University of Minnesota, Minneapolis, 1949-1950.
Research chemist Upjohn Company, Kalamazoo, 1950-1956.
Assistant professor of University South Carolina., 1956-1957. Senior chemist Southern Research Institute, Birmingham,1957-1959, section head, 1959-1966, head medicinal chemical division, 1966-1990, distinguished scientist, 1990.
Speaker 12th International Cancer Congress, 3d International Conference on Prevention of Cancer. Named to Hall of Fame, Chapin, South Carolina.
United States and foreign Patentee for medicinal agents.
Pioneer in carbocyclic analogs of purine and pyrimidine nucleosides including carbodine, 2"-CDG and aristeromycin. Synthesized anti-cancer drugs dacarbazine, clomesone and BCTIC. Synthesized antifungal and antibactierial agents including the first monocyclic 1,2,5-Selenadiazoles and triazenylimidazole esters.
Synthesized antiviral and anticancer agents including MCTIC and MTIC (which laid the foundations for mitozolomide and temozolomide) and chloroethylnitrosocarbamates. Synthesized cancer chemopreventative retinoids such as retinoylamino acids, retinyl ethersand 4-oxoretinoic acid derivatives.
With Chemist Office Science Research and Development, 1943—1945. Postdoctoral fellow University Minnesota, Minneapolis, 1949—1950. Research chemist Upjohn Company, Kalamazoo, 1950—1956.
Assistant professor University South Carolina, 1956—1957. Senior chemist Southern Research Institute, Birmingham, 1957—1959, section head, 1959—1966, head medicinal chemical division, 1966—1990, distinguished scientist, since 1990. Speaker 12th International Cancer Congress, 3rd International Conference Prevention Cancer.
Fellow: American Association for the Advancement of Science. Member: European Retinoid Research Group, International Society Antiviral Research, American Pharmaceutical Association, International Acquired Immune Deficiency Syndrome Society, New York Academy of Sciences, International Society Nutrition and Cancer, American Association Cancer Research, American Chemical Society, Alpha Chi Sigma, Pi Mu Epsilon, Phi Lambda Upsilon, Phi Beta Kappa, Sigma Xi.
Married Elaine Curtis, October 5, 1950. Children: Robin T., Nancy G., Priscilla B. Bachelor of Science, University of Southern California, 1943.
