Background
Yap, Yee Guan was born on December 19, 1967 in Mentakab, Pahang, Malaysia. Arrived in England, 1985. Son of Boon Kian Yap and Geok Hong Tan.
(In recent years there has been considerable interest in t...)
In recent years there has been considerable interest in the diagnosis and understanding of ventricular repolarisation, particularly the QT interval prolongation and abnormal T and T/U wave morphology associated with torsades de pointes. Advances in ion channel cloning have greatly improved our understanding of the role of ionic channels in mediating cardiac repolarisation. Unfortunately, it is increasingly recognised that a number of drugs, both those associated with altering repolarisation, and others for non-cardiac conditions can increase the propensity for polymorphic ventricular tachycardia, syncope and even ventricular fibrillation and sudden death. In this volume, arrhythmia specialists from St. George's Hospital Medical School, London discuss the mechanisms behind QT prolongation and torsades de pointes. They focus particularly on the risk of individual cardiac and non-cardiac drugs in provoking long QT syndrome, providing a comprehensive review which will be useful for all electrophysiologists treating polymorphic ventricular tachycardias, and will expose important regulatory issues for pharmaceutical authorities and for the wider medical community.
http://www.amazon.com/gp/product/1405118385/?tag=2022091-20
(To most cardiologists, the long QT syndrome is a relative...)
To most cardiologists, the long QT syndrome is a relatively rare congenital and familial syndrome that affects children or young adults. However, in addition to congenital LQTS there is a series of acquired forms of the syndrome, usually resulting from exposure to drugs that extend the duration the QT interval. This prolongation may be the primary pharmacodynamic action of the drug, however a plethora of other drugs, including some types of antibiotic, antipsychotics, antidepressants, antimalarials and antihistamines may provoke QT interval prolongation. The aim of the Clinical Approaches to Tachyarryhthmias series is to update the physician, cardiologist, and all those responsible for the the care of patients with cardiac arrhythmias. In this volume, Dr. Yap and Dr. Camm expose the data implicating a large number of drugs as potential QT prolongators.
http://www.amazon.com/gp/product/0879934689/?tag=2022091-20
Yap, Yee Guan was born on December 19, 1967 in Mentakab, Pahang, Malaysia. Arrived in England, 1985. Son of Boon Kian Yap and Geok Hong Tan.
Bachelor in Medical Science with honors, University Nottingham, 1990. Bachelor of Medicine, Bachelor of Surgery, University Nottingham, 1992. Doctor of Medicine, University London, 2005.
House surgeon University Hospital, Nottingham, 1992-1993. House physician Southampton General Hospital, England, 1993. Senior house officer Cardiothoracic Center, Liverpool, 1993-1994, St. George's Hospital, London, 1994-1996, British Heart Foundation research fellow in cardiology, 1997-2000, interventional fellow, senior specialist registrar in cardiology, 2000—2005.
Associate professor, head department medicine and cardiology section University Putra, Malaysia, since 2005. Consultant cardiologist and interventionist department cardiology, cardiothoracic unit Serdang Hospital, Selangor, since 2005. Consultant and interventional Cardiologist Prince Coua Medical Center, Kuala Lumpor, Malaysia.
(In recent years there has been considerable interest in t...)
(To most cardiologists, the long QT syndrome is a relative...)
Fellow Academy Medicine Singapore, Royal College Physicians Glasgow, Royal College Physicians Edinburgh, European Society Cardiology, Society Cardiovasc. Angiography and Interventions, American Heart Association.
Married Wendy Lim, November 29, 1998. Children: Sebastian, Oliver, Dominic.