Crawford at the Angel Ball, 2007.
He lived in Bloomington, Minnesota for four years and then graduated high school from Trinity Christian Academy.
Crawford played football and golf in high school.
After high school, he moved to Malibu, California, to attend Pepperdine University, where he studied broadcast journalism. He struggled to identify a career path, vacillating among advertising, business, and communications majors. As a university student he was a Sigma Nu fraternity.
While studying at Pepperdine, Chace wanted to be a doctor like his father.
In 2007, Crawford landed the role of Nate Archibald on The CW's Gossip Girl.
Crawford played British singer Leona Lewis's boyfriend in the video for her song "I Will Be". The video was released in January 2009. The same year, Crawford was named "Summer's Hottest Bachelor" by People. He has also done a public service announcement for Do Something's Teens for Jeans campaign.
Crawford signed on to play a lead role as a drug dealer named White Mike in the film Twelve, directed by Joel Schumacher. The film, based on Nick McDonell's novel of the same name, premiered at Sundance Film Festival on January 31, 2010.
Crawford was scheduled to play the lead in the remake of Footloose but dropped out. Zac Efron was also tied to the project at one point before dropping out as well. Kenny Wormald was eventually cast for the role.
In June 2010, it was confirmed that Crawford will join the indie flick Peace, Love, & Misunderstanding alongside Jane Fonda and Catherine Keener. He will portray a war-protesting butcher, Cole, who is a love interest of Fonda's character's daughter.
In May 2011, it was announced that Crawford had been cast in the romantic comedy film Responsible Adults opposite actress Katie Holmes, written by Alex Schemmer and directed by Jon Poll.