Diploma in physics, Technische Hochschule, Karlsruhe, Germany, 1959. Doctor Eng, Technische Hochschule, Karlsruhe, Germany, 1965. Habilitation, University Heidelberg, Germany, 1969.
Doctor Medicine and Surgery (honorary), University Siena, Italy, 1994.
Research assistant Technische Hochschule Karlsruhe, 1959-1964, University Heidelberg, 1964-1969, university lecturer physiology, 1969-1973, professor, since 1973, director physiology central nervous system department, 1971-1999. Visiting professor Monash University, Melbourne, Australia, 1973-1974, Medical University, Wuhan, China, 1983, 92, University Siena, Italy, 1985. Editor-in-chief Neuroscience Letters, Elsevier Public Company, Amsterdam, The Netherlands, since 1975, Der Schmerz Springer, Heidelberg, 1987-1992.
Editor The Clinical Journal Pain, Raven, New York, 1985-1999.
Member International Association for Study of Pain (founding, council 1981-1987), German Society for Study of Pain (founder, president 1985-1996. Honorary), Society for Neurosci., Austrian Pain Society (honorary), European Federation Pain Society (founder, president 1996-1999), Romanian Pain Society (honorary), Slovak Medical Association (honorary), InterPain (honorary).
Married Herta Lages, (divorced 1986). Children: Christoph Johannes, Frank Martin. Married Dagmar Drüll, 1987.