Background
Costa, Max was born on January 10, 1952.
(Metal Carcinogenesis Testing explains fundamental princip...)
Metal Carcinogenesis Testing explains fundamental principles of metal carcinogenesis as they are currently understood, and provides detailed practical descriptions of rapid and inexpensive in vitro assay methodology presently in use for the detection of potentially carci nogenic metals and their compounds. Mounting experimental evidence has suggested that a number of metals and their compounds are potentially carcinogenic to humans. Since humans are exposed to these potentially carcinogenic metals in industrial situations and through environmental pollution, it is essential that experimental protocols be available to identify the specific metal compounds that are potentially carcinogenic. This book affords a thorough description of the various carcinogenesis test systems available for metals, centering on those that are rapid, inexpensive, and most reliable. The principles are discussed at the level of human exposure, of animal studies, and of research in vitro. Additionally, the molecular mechanisms of metal-induced cancer are considered at each ofthese three levels.In large part, the emphasis rests on the use of in vitro, biochemical and bacterial studies, including tissue culture, because these methods are the basis of the rapid and inexpensive screening of potentially carcinogenic substances.
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administrator pharmacology educator
Costa, Max was born on January 10, 1952.
Bachelor of Science in Biology, Georgetown University, 1974. Doctor of Philosophy in Pharmacology, University Arizona, 1976.
Research assistant National Institute of Mental Health, Bethesda, Maryland, 1970-1972, Laboratory Tumor Cell Biology, National Cancer Institute, Bethesda, 1972-1974. Research associate, division radiation oncology University Arizona School of Medicine, Tucson, 1976. Assistant professor laboratory medicine University Connecticut School Medicine, Farmington, Connecticut, 1977-1979.
Assistant professor department pharmacology and toxicology College Medicine, Texas A & M University, College Station, Texas, 1979-1980. Assistant professor department pharmacology University Texas Medical School, Houston, 1980-1981, associate professor department pharmacology, 1981-1985, professor department pharmacology, 1985-1986. Professor environmental medicine and pharmacology New York University Medical Center, New York City, 1986-1992.
Deputy director Institute Environmental Medicine, New York University Medical Center, 1986-1992, professor, chairman department environmental medicine, since 1993. Director The Nelson Institute Environmental Medicine, Tuxedo, New York, since 1993. Burroughs Wellcome professor University South Alabama College Medicine, 1996.
Expert witness testified United States Congressional Hearing, 1979, Department Labor, Occupational Safety and Health Administration, 1990. Consultant Amax, Inc., 1977-1980, NiPera, 1981, 82. Visiting professor Kurume University, Japan, 1989.
Invited lecturer, speaker National Cancer Center Research Institute, Tokyo, Kitasato University, Tokyo, Shizuoka College, Japan, Kurume University, Japan, Robert Wood Johnson Medical School, New Jersey, Temple University, Pennsylvania, University Milan, Italy, University Tennessee, University California, Rutgers University, Cornell University, Brown University, and numerous others.
(Metal Carcinogenesis Testing explains fundamental princip...)
Member American Association for the Advancement of Science, American Society Cell Biology, American Society Biochemistry and Molecular Biology, American Society Pharmacology and Experimental Therapeutics, Society Toxicology, American Association Cancer Research, International Association Bioinorganic Scientists, International Association Environmental Analytical Chemistry.