Background
PRAVDIN, Nikolay was born in 1882.
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Nikolay Sergeyevich PRAVDIN
Edit ProfileEducation
1912 graduate Natural Sciences Department, then Medical Faculty, Moscow University.
Career
1914-1918 in Russian Army. From 1918 continued medical work in Moscow. 1920 defended doctor’s thesis on "Matscsta, matsestinskiyc vanny i ikh vliyaniye na krovoobrashcheniyc” (Matscsta, Matsesta Baths and Their Effects on the Circulations.
From 1927 head Toxicological Laboratory, Institute of Labor Protection, People's Commissariat of Labor (now a laboratory of the Institute of Labor Hygiene and Occupational Diseases, Union of the Soviet Socialist Republics Academy of Medical Sciences). From 1943 professor; specialized in experiments on maximum permissible concentration of chemicals in the air of industry premises and the operative mechnism of industry poisons. Proposed that the degree of toxicity of chemical substances be judged by the concentration approaching the danger threshhold, and that the hazard of acute poisoning be judged by the toxic action zone.
Foreign studying the operative mechanism of toxins stressed the need of studying the dystrophy of biochemical processes within the body, especially dystrophy of the enzyme systems involved in oxidation processes. Did valuable research on the operative mechanism of carbon monoxide. Demonstrated that in this case a considerable role was played by dystrophy of the enzyme systems, especially the tissue respiration of the brain as a result of carbon monoxide’s effects on oxidation enzymes.
In his latter years specialized in combined effects of industry poisons and mechanism of chronic poisoning. First to use conditioned reflex methods for toxicological research. Made first attempt to classify industry poisons along production lines.
Wrote over 60 works.
