In 1960 Rostislav Sergeevich Karpov graduated from the Medical Faculty of Tomsk Medical Institute and became an intern at the Faculty Therapy Clinic. In 1962 Rostislav Sergeevich entered postgraduate study at the Department of Faculty Therapy, after which in 1965 he defended his thesis on the topic "Comparative diagnostic value of some immunological and biochemical tests in recognizing the activity of the rheumatic process in patients with cardiac defects."
From 1965 to 1966 Rostislav Sergeevich Karpov was a physician at the Faculty Therapy Clinic. From 1966 to the present time he works at the Department of Faculty Therapy of the Tomsk Medical Institute as an assistant (1966-1972), associate professor (1972-1977), professor (1977-1979), head of the department (1979 to present).
In 1974 he defended his PhD thesis on "Clinical and immunological characteristics of recurrent adult rheumatism".
Since 1980 Rostislav Sergeevich Karpov has been working as deputy director for science, and since 1985 - director of the Cardiology Research Institute of the Tomsk Scientific Center of the Siberian Branch of the Russian Academy of Medical Sciences (formerly SF of the All-Union Scientific Center of the Academy of Medical Sciences of the USSR).
Since 1980 to the present time Rostislav Sergeevich manages the department of atherosclerosis and chronic ischemic heart disease of this institute. From 1985 to 1986, he served as the director of the Siberian branches of the All-Union Scientific Centers of Oncology, Cardiology, and Mental Health of the USSR Academy of Medical Sciences. From 1986 to the present time he is chairman of the Presidium of the Tomsk Scientific Center of the Siberian Branch of the Russian Academy of Medical Sciences.
In 1980 Rostislav Sergeevich Karpov was elected a corresponding member of the Academy of Medical Sciences of the USSR, and in 1982 - a full member of the USSR Academy of Medical Sciences (now RAMS). R.S. Karpov is the Chief Cardiologist of the Siberian Federal District (2002), Vice President of the All-Russian Scientific Society of Cardiology (1999), Vice President of the Scientific Society of Arterial Hypertension (1999), member of the European and International Societies of Cardiology, Honorary Member of the Bulgarian Cardiology Society (1987), Chairman of the Tomsk Regional Society of Cardiology (1980), member of the Coordinating Council of the Russian Scientific and Technical Program "Scientific Priorities in Health Care", Chairman of the Scientific Council of the Scientific Research Institute of Cardiology TSC SB RAMS (1980), Chairman of the Dissertation Council on Cardiology (1986), Chairman of the Problem Commission "Cardiology" of the Interdepartmental Scientific Council on Medical Problems of Siberia, the Far East and the Far North.