Background
Palay, Sanford Louis was born on September 23, 1918 in Cleveland. Son of Harry and Lena (Sugarman) Palay.
(The origins of this book go back to the first electron mi...)
The origins of this book go back to the first electron microscopic studies of the central nervous system. The cerebellar cortex was from the first an object of close study in the electron microscope, repeating in modern cytology and neuroanatomy the role it had in the hands of RAMON y CAJAL at the end of the nineteenth century. The senior author vividly remembers a day early in 1953 when GEORGE PALADE, with whom he was then working, showed him an electron micrograph of a cerebellar glomerulus, saying "That is what the synapse should look like. " It is true that the tissue was swollen and the mitochondria were exploded, but all of the essentials of synaptic structure were visible. At that time small fragments of tissue, fixed by immersion in osmium tetroxide and embedded in methacrylate, were laboriously sectioned with glass knives without any predetermined orientation and then examined in the electron microscope. After much searching, favorably preserved areas' were studied at the cytological level in order to recognize the parts of neurons and characterize them. Such procedures, dependent upon random sections and uncontrollable selection by a highly erratic technique of preservation, precluded any systematic investigation of the organization of a particular nucleus or region of the central nervous system. It was difficult enough to distinguish neurons from the neuroglia.
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(This book represents the most complete and authoritative ...)
This book represents the most complete and authoritative description on the fine structure of the nervous system available in a single volume. Beginning with background material on the neuron, the book then examines specific portions of the nerve cell, and of the various supporting cells. Structure is first described in a general fashion, followed by detailed coverage of the fine structure of each component, with full discussion of how the structural features relate to their functions. Extensively revised and rewritten, this book will bring readers up to date with the many important developments that have taken place since publication of the previous edition. It includes over 130 electron micrographs and line drawings, many of which are new to this edition.
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Palay, Sanford Louis was born on September 23, 1918 in Cleveland. Son of Harry and Lena (Sugarman) Palay.
AB, Oberlin College, 1940. Doctor of Medicine (Hoover prize scholar 1943), Western Reserve University, 1943.
Teaching fellow medicine, research associate anatomy, Western Reserve U., Cleveland, 1945-1946;
National Research Council fellow medical science, Rockefeller Institute, 1948;
visiting investigator, Rockefeller Institute, 1953;
from instructor anatomy to associate professor anatomy, Yale University, 1949-1956;
chief section neurocytology, laboratory neuroanatomical science, National Institute Neurological Diseases and Blindness, National Institutes of Health, Washington, 1956-1961;
chief laboratory neuroanatomical science, National Institute Neurological Diseases and Blindness, National Institutes of Health, 1960-1961;
Bullard professor neuroanatomy, Harvard, Boston, 1961-1989;
professor emeritus, Harvard, Boston, since 1989. Linnean Society lecturer, London, 1959. Visiting investigator Middlesex Hospital (Bland-Sutton Institute), London, England., 1961.
Phillips lecturer Haverford College, 1959. Ramsay Henderson Trust lecturer U. Edinburgh, Scotland, 1962. George H. Bishop lecturer Washington University, St. Louis, 1990.
Distinguished Scientist lecturer Tulane University School Medicine, 1969, 75. Visiting professor U. Washington, 1969. Rogowski Memorial lecturer Yale, 1973.
Distinguished lecturer biological structure U. Miami, 1974. Distinguished Scientist lecturer U. Arkansas, 1977. Distinguished scholar-in-residence department biology Boston College, Chestnut Hill, Massachusetts, since 1994.
Other Distinguished lectureships. Visiting professor U. Osaka, Japan,1978, National U. Singapore, 1983. Special visiting professor U. Osaka, 1988.
Chairman.study section on behavioral and neural science National Institutes of Health, 1984-1986. Member fellowship board National Institutes of Health, 1958-1961, cell biology study section, 1959-1965, advising committee high voltage electron microscope resources, 1973-1980, member review committee behavioral and neurological science fellowships, 1979-1986. Chairman Gordon Research Conference Cell Structure and Metabolism, 1960.
Associate Neuroscis. Research Program, 1962-1967, consultant associate, since 1975. Member anatomical science training committee National Institute General Medical Sciences, 1968-1972. Member science advising committee Oregon Regional Primate Research Center, 1971-1976.
(This book represents the most complete and authoritative ...)
(The origins of this book go back to the first electron mi...)
Served to captain Medical Corps Army of the United States, 1946-1947. Fellow American Academy Arts and Sciences. Member National Academy of Sciences, American Association Anatomists (chairman nominating committee 1964, member executive committee 1970-1974, anatomical nomenclature committee 1975-1978, president 1980-1981, Henry Gray award 1990), Histochem.
Society, Electron Microscope Society of America, American Association for the Advancement of Science, American Society Cell Biology (program committee 1975), International Society Cell Biology, Society for Neurosci. (Gerard award 1990), Washington Society Electron Microscopy (organizing committee, secretary-treasurer 1956-1958), Society Francaise de Microscopie Electronique (honorary), Royal Microscopical Society (honorary), Golgi Society (honorary), Anatomical Society Gr. Britain and Ireland (honorary), Cajal Club (president 1973-1974), American Philosophical Society, Phi Beta Kappa, Sigma Xi, Alpha Omega Alpha.
Married Victoria Chan Curtis, 1970 (divorced November 1990). Children: Victoria Li-Mei, Rebecca Li-Ming.