In 1970, Tatyana Alexandrovna Mamchik graduated from the Leningrad Sanitary and Hygenic Medical Institute (now Saint Petersburg State Medical Academy).
Tatyana Alexandrovna Mamchik worked as a sanitary physician in the Voronezh region sanitation and epidemiology station during 1970-1972. In 1972-1975, she was a chief of the department of communal municipal hygiene, and an alternate of the chief physician during 1975-1989. Since 1989 she has been working as a chief physician of Voronezh region center for prevention and control of AIDS and infectious diseases.
Tatyana Mamchik is the author of more than 70 publications on the problem of changing of the immune status under the influence of the anthropogenic environment, including the book "Habitat and the immune status of the population" (Voronezh, 2004).