Vassili Ph.
Vassili Philippovich Pastushenko was born on May 22, 1943, in Orsha, in the Vitsyebskaya Voblasts' of Belarus. His scientific career developed within the Soviet and later European traditions of theoretical and experimental bioelectrochemistry. He became associated with the Frumkin Institute of Electrochemistry of the USSR Academy of Sciences in Moscow, where he worked on the physical chemistry of biological membranes and excitable systems before continuing his research in Austria.
Pastushenko studied physics and completed graduate-level scientific training in the Soviet Union. He defended a candidate thesis in chemical sciences in 1969 and later defended a doctoral thesis in biophysics at Moscow State University in 1987. His documented academic training and subsequent research brought together physical chemistry, electrochemistry, membrane biophysics, electrophysiology, and mathematical modeling.
Pastushenko began his research career in 1966 at the Institute of Electrochemistry of the USSR Academy of Sciences in Moscow, later known as the A. N. Frumkin Institute of Electrochemistry. His early work with collaborators including Yuri A. Chizmadzhev and Vladislav S. Markin examined ion transport, membrane potentials, nerve-impulse propagation, lipid-bilayer conductivity, and theoretical models of excitable biological membranes. He continued at the institute through 1991 and contributed to studies of electrical breakdown, pore formation, membrane electroporation, and electrophoretic behavior of long molecules. In 1991 he moved to Austria and joined the Institute of Biophysics at Johannes Kepler University of Linz, where he worked as a guest professor and later as a senior and leading scientific researcher. His Linz research included ion-channel signal analysis, atomic-force and single-molecule microscopy, membrane domains, DNA and membrane mechanics, and the imaging of biomolecular interactions. He also pursued theoretical work on electro-osmotic oscillators, including the Uppsalator, and applied statistical methods to scientific data analysis.
Co-developed theoretical and experimental work on the electrical behavior, excitability, and breakdown of biological and artificial lipid membranes.
Contributed to the development and application of single-molecule and atomic-force microscopy methods for studying membrane domains, ion channels, DNA, and biomolecular interactions.
Published theoretical analyses of electrophoretic transport, electro-osmotic oscillations, and statistical methods for scientific data analysis.
(Research article on the imaging, organization, mobility, ...)
2000The electrical breakdown of cell and lipid membranes: the similarity of phenomenologies
(Co-authored study comparing electrical breakdown in biolo...)
1987(Co-authored study of membrane potentials and short-circui...)
1969(Co-authored methodological study presenting a parameter-f...)
1997(Co-authored study applying image-processing methods to im...)
2006(Theoretical analysis of the mobility of long linear molec...)
1991(Theoretical analysis of acceleration and deceleration reg...)
2007(Co-authored study of impulse propagation and interaction ...)
1969Following single antibody binding to purple membranes in real time
(Research article on real-time observation of single-antib...)
2004(Theoretical study of DNA conformation, tension, and separ...)
1991(Co-authored theoretical analysis of relaxation oscillatio...)
1980(Theoretical study of background conductivity in lipid bil...)
1984(Article presenting a statistical treatment of empirical c...)
2009(Co-authored review examining nerve-cell electrical proper...)
1977(Co-authored review of the physical and electrochemical me...)
1975(Co-authored scientific monograph with Vladislav S. Markin...)
1987Pastushenko's documented professional and scientific connections include collaborators at the Frumkin Institute of Electrochemistry and Johannes Kepler University of Linz. His long-term research collaborations included Yuri A. Chizmadzhev and Vladislav S. Markin on excitable membranes and nerve impulses, and Peter Hinterdorfer and other biophysicists on atomic-force microscopy and single-molecule studies.
