Kan Nai-kuang graduated from the School of Economics, Lingnan University (Canton Christian College), Canton, in 1922. In 1928 he attended the University of Chicago as a research fellow, and toured Europe to study political conditions, 1929.
Mr. Kan was an instructor at Lingnan University in 1922-1923. In 1924 he was appointed instructor in political science at the Whampoa Military Academy and concurrently compiler and secretary of the Central Party Headquarters, Canton. Kan Nai-kuang was elected member of the Central Executive Committee at the second plenary session in 1925.
Later he served successively as director of merchants' department, youth department, and farmers' department of the Central Party Headquarters, member of the Central Political Council, member of Executive Committee of Guangdong Provincial Party Headquarters and concurrently director of publicity department.
In 1926 Mr. Kan was appointed member of the Control Yuan of the Nationalist Government. Between 1926 and 1927, he served successively as member of Guangdong Provincial Government, inspector of administrative affairs in Southern Guangdong, assistant proctor of the National Chun-shan University at Canton, director of the Canton Kuo Min News and Canton Republican Daily News.
Upon the establishment of the National Government in Nanjing in 1927, he was appointed director of the farmers' department of the Central Party Headquarters and Commissioner of Agriculture and Labor of Jiangsu Provincial Government, but declined both appointments owing to preparations to go abroad to study. In December 1927 Kan Nai-kuang held the post of a chairman of the Canton Municipal Government.
Mr. Kan devoted himself to authorship in Shanghai after return to China in 1929. He was re-elected member of the Central Executive Committee at the 4th Plenary Session which took place in 1931. Kan Nai-kuang was appointed vice-minister of Interior of the National Government, in June, 1932 which post he held until 1935 and he was concurrently an acting minister of Interior from October, 1934, to January, 1935.
Later he served as a director of the Political Affairs Department of the Wuchang Headquarters of the President of the Military Affairs Commission. Since December 1935 Mr. Kan became a commissioner of Civil Affairs of Zhejiang Provincial Government.