She studied under Hans Heyerdahl in Oslo (1896) and under Christoph Roth in Munich (1898-1899) before she continued her studies in Paris.
She completed her education in Italy in 1905. Tupsy Clement had a broad artistic background before she met the Danish painter G.F. The couple married in Rome in 1902 and thereafter settled in Denmark. In addition to portraits, Tupsy painted flowers, exteriors and landscapes.
Her painting Two girls playing at Skagen Beach was once owned by King Christian X who spent his summers at Klitgaarden in Skagen.
From 1920, the couple spent most of their summers in Italy. G.F. Clement died in 1933 and Tupsy in 1959.
They had no children.