In 1929 Leisle graduated from Voronezh Agricultural Institute, the Faculty of Agronomy.
Victor Filippovich Leisle was a scientist. His scientific interests included the introduction of new plants into the culture; the study of plants in connection with the problem of fodder for animal husbandry; the physiology and breeding of essential oil and rubber plants.
Victor Filippovich Leisle participated in the Civil War in 1918-1920. Firstly he was in the unit of V.I. Kikvidze, and then in the part of the 1st Cavalry army, fighting in the Donbass, near Rostov, in the North Caucasus.
In 1924-1941 he was a researcher of the Botanical Experimental Station at Voronezh Agricultural Institute, Voronezh branch of the State Institute of Arid Regions. At the same time in 1929-1930, he was an assistant of the Bureau of Geobotany and Plant Physiology of the Institute of Soil Melioration. Since 1930 he was an assistant, lecturer and professor. In 1949-1977 he was the head of the department of Botany at Voronezh Agricultural Institute.